RESEARCH AND TEACHING POSTDOCTORAL POSITION
AT UCSF IN STEM CELL BIOLOGY
The Nystul Laboratory at the University of California San Francisco is seeking applicants who are interested in a postdoctoral fellowship that combines intensive research and undergraduate teaching experiences. The successful applicant will compete for independent funding through the UCSF IRACDA program funded by the NIGMS. IRACDA scholars must be a US citizen or permenent resident.
With our recent studies, we are well-positioned to investigate several different directions related to understanding the mechanism of competition for the niche in epithelial stem cell maintenance and the mechanism by which stem cell and daughter cell fates are segregated. These projects build on our recent publications describing (1) our discovery that the epithelial follicle stem cells of the Drosophila ovary undergo neutral competition for niche occupancy in wildtype tissue; (2) the results of a screen in which we have identified several new mutations that cause “hypercompetition” for niche occupancy; and (3) our discoveries of mechanisms that govern the follicle stem cell niche and prefollicle cell differentiation. The project will use cell biological and genetic approaches to discover fundamental mechanisms that regulate epithelial stem cells in vivo. The primary model system will be the Drosophila ovary, and our ongoing collaborations provide the opportunity to investigate ideas generated from our work with Drosophila in mouse models and human cell lines. The project will also include opportunities to develop skills in single cell RNA sequencing, live imaging, MatLab programming, and statistical analysis related to neutral competition modeling.
We are seeking candidates who are creative and highly motivated, and have a strong foundation in genetics and cell biology. Candidates must have a recent PhD or MD/PhD and less than 3 years of prior postdoctoral experience. Salary is commensurate with experience. The position is available starting Spring 2019 and will be open until filled. Interested applicants should contact Todd Nystul at [email protected] with a letter describing your interest and previous experience as well as a CV including the names and contact information of 3 references.